Oral contraceptives for pain associated with endometriosis

Advantages of the association of resveratrol with oral contraceptives for management of endometriosis-related pain

BACKGROUND The effect of resveratrol on the management of endometriosis-related pain was investigated in 12 patients who failed to obtain pain relief during use of an oral contraceptive containing drospirenone + ethinylestradiol. METHODS AND RESULTS The addition of 30 mg of resveratrol to the contraceptive regimen resulted in a significant reduction in pain scores, with 82% of patients report...

Elagolix: a promising oral GnRH antagonist for endometriosis-associated pain

Some Biochemical Alternations Associated with Oral Contraceptives

An excess intake of vitamin D2 can result in mobilization of calcium in the skeleton and increase the serum calcium level. This calcium is taken up by soft tissues such as arteries. The risk of calcium builds up in arteries, a significant component of atherosclerotic plaque. Many researches clarify the relationship between oral contraceptives and atherosclerosis. This study aims to evaluate the...

hormonal treatment for endometriosis associated pelvic pain

background: endometriosis is a common gynecological problem associated with chronic pelvic pain. objective: to evaluate the effectiveness of current hormonal treatments of endometriosis associated pain. materials and methods: randomized controlled studies identified from databases of medline and cochrane systemic review groups were pooled. 7 rcts were recruited for evaluation in this review. da...

Combining oral contraceptives with a natural nuclear factor-kappa B inhibitor for the treatment of endometriosis-related pain

Endometriosis is a chronic disease in which a persistent state of heightened inflammation is maintained by nuclear factor-kappa B (NF-κB) activation. The progestins present in oral contraceptives are potent inhibitors of NF-κB translocation to cell nuclei, while Pycnogenol® (Pinus pinaster) acts by blocking post-translational events. In this study, the effects of Pycnogenol on pain scores were ...